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CHOP Researchers Find Effective Combination of Therapies for Managing Mitochondrial Disease

Study is first to demonstrate how one specific combinational therapy may provide measurable benefits to patients with mitochondrial respiratory chain disorders, which currently lack FDA-approved therapies.

Experts at Children’s Hospital of Philadelphia Describe Types of Rashes Associated with MIS-C

CHOP researchers describe different types of rashes they have seen in patients diagnosed with the COVID-19-related inflammatory syndrome.

CHOP Researchers Find NTRK Fusions More Common than Expected in Pediatric Tumors

CHOP researchers have found that NTRK fusions are more common than expected in pediatric tumors, which could lead to better screening and treatment.

CHOP Researchers Characterize Shared Pathways in Epilepsy and Autism

In a new study, CHOP researchers integrate data regarding how the conditions present clinically with data on protein-protein interactions.

CHOP and Penn Researchers Identify Nanoparticles that Could Be Used in Therapeutic mRNA Delivery before Birth

Dr. Peranteau in the laboratory

In a proof-of-concept study, CHOP and Penn researchers have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy.

FDA Approves Drug for Rare Form of Pediatric Cancer

The FDA has approved a treatment that targets ALK mutations in relapsed, refractory ALK-positive anaplastic large cell lymphoma.

Case Study: Rotationplasty for Osteosarcoma

Liam playing soccer

Van Nes rotationplasty surgery for osteosarcoma is a “functional amputation” in which the the foot is rotated 180 degrees on the vertical axis and the ankle becomes a functioning knee joint.

Endocrinology Chief Diva D. De León-Crutchlow, MD, MSCE, Featured in Her Home Country of Panama

Diva D. De León-Crutchlow, MD, MSCE in the lab

In a special segment broadcast in Panama, Diva D. De León-Crutchlow, MD, MSCE, recalled her path from her home county to her role as Chief of the Division of Endocrinology and Diabetes and Director of the Congenital Hyperinsulinism Center at Children's Hospital of Philadelphia (CHOP).

CHOP Psychiatrist Discusses Big Feelings About COVID-19 on CNN

Dr. Wanjiku Njoroge, medical director of the Young Child Clinic, gave parents tips on how to talk to kids about COVID-19.

CHOP Teams Explore Experimental Treatments for COVID-19

As COVID-19 continues to spread worldwide, teams at Children’s Hospital of Philadelphia are using a collaborative approach to identify and test potential treatments.

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