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Transverse Vaginal Septum Cause of Urinary Retention

A 15-year-old female’s inability to void brought her to the ED. It took a renal bladder ultrasound and a pelvic MRI to find the cause: transverse vaginal septum.

Less Invasive Management of a Large Pneumatocele

In this article, we review a case of a preterm infant with severe bronchopulmonary dysplasia (BPD), a history of S. aureus pneumonia, and subsequent large pneumatocele, managed with a less typical treatment modality.

Integrating Precision Medicine into Standard of Care for Children with Thyroid Cancer

Read this case study about integrating precision medicine into the standard of care for children with thyroid cancer.

Two Focal Lesions: Extra Rare Cases Not So Rare at CHOP

The Congenital Hyperinsulinism Center at Children’s Hospital of Philadelphia, with a high volume of approximately 80 congenital hyperinsulinism (HI) cases a year, sees a large share of unusual cases.

Snapshot Science: Is a New FDA-Approved Transcatheter Pulmonary Valve Safe and Effective for Patients?

Yes! According to three clinical trials led by CHOP, the Harmony TPV can replace the pulmonary valve and treat pulmonary regurgitation — all without surgery.

CHOP Treats 500th CAR T Patient

CHOP has treated its 500th patient with CAR T-cell immunotherapy, a “living drug” that harnesses the power of a patient’s own immune system to fight cancer.

In Celebration of the Abraham Accords, CHOP Hosts Pediatric Experts from the United Arab Emirates (U.A.E.) and Israel to Share Knowledge, Research

A year after the signing of the Abraham Accords leaders and clinicians from Children's Hospital of Philadelphia (CHOP) hosted a meeting to share knowledge and research with pediatric experts from CHOP, the U.A.E. and Israel.

A Comprehensive Approach to Beckwith-Wiedemann Syndrome

Beckwith-Wiedemann syndrome (BWS) is a complex multisystem overgrowth and cancer predisposition disorder that affects about 1 in 10,000 live births.

Legg-Calve-Perthes Disease: A Case Study

When A.L. was 11 years old, he complained of pain in his left hip. The pain subsided, but a week and a half later, A.L. came home crying and barely able to walk. The pain in his hip had become “excruciating.”

Positive Preliminary Data on CRISPR Treatment for Blood Diseases

A collaborative team of researchers, including Dr. Stephan Grupp, recently presented preliminary data showing that a CRISPR-based gene-editing therapy for inherited blood disorders is safe and effective.

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