The Cancer Center at Children’s Hospital of Philadelphia (CHOP) provides the newest, most advanced research and the most innovative treatments for all types of childhood cancer. CHOP has the largest pediatric oncology research program in the United States, and physician-researchers translate scientific discoveries quickly into clinical therapies.

Why Choose CHOP Cancer Center

• Led clinical trials into the first form of CAR T-cell therapy to be approved by the U.S. Food and Drug Administration (FDA) for the treatment of relapsed and refractory pediatric acute lymphoblastic leukemia (ALL).
• Internationally recognized for excellence in pediatric leukemia and lymphoma treatment. No other hospital in the United States has our depth of expertise in pediatric liquid cancers, cell therapy and transplantation.
• An experienced proton therapy team that has treated more than 800 patients, and is uniquely equipped to care for children who are transitioning their cancer care from other hospitals.
• The world’s leading treatment center for neuroblastoma, the most common pediatric solid tumor outside the brain.
• One of the largest brain tumor centers in the United States, offering an endoscopic endonasal approach for some tumors.

Conditions we treat

Specialized clinical and research programs

Center for Childhood Cancer Research

Our research focus is on cancer therapies, prevention and treatment of the physical and psychological complications of those therapies.

Cancer Immunotherapy Program

Our experts in the Cancer Immunotherapy Program helped develop the first national and international clinical trials for an immunotherapy known as chimeric antigen receptor (“CAR”) T-cell therapy for children.

Roberts Proton Therapy Center

The Cancer Center offers proton therapy for children in collaboration with the Hospital of the University of Pennsylvania at the Roberts Proton Therapy Center.

Blood and Marrow Transplant Program

Our team has extensive expertise in autologous and allogeneic blood and bone marrow transplant. Our allogeneic program utilizes alternative donor options such as unrelated donors and partially matched related donors.

Neuro-Oncology Program

The Neuro-Oncology Program is one of the largest pediatric programs dedicated to the care of children with brain and spinal cord tumors.

Solid Tumor Program

Our Solid Tumor Program is one of the few pediatric cancer programs in the United States with a team dedicated to care of children with solid tumors.